Friday, 20 February 2015

General Answers to Questions about Animal Models

Transgenic animal models are a valuable tool for exploring many biological questions, for better understanding diseases, and for producing new drugs to save human lives. It is fair to say that without the use of animal’s models, the possibility of medical breakthrough is significantly reduced. Transgenic animals allow for more efficient scientific advancement due to the inexpensive cost of housing lab animals, their short life cycles, and their rapid reproduction rates.

Why are we using animals as models to investigate human diseases?

Many animals share biological similarity with humans and the biological similarity of animals   allow closer approximation to a human response. However, animal models of human diseases are only ideal for investigating human disease at a given time. Even though the specific details of how the future therapy are still not clear, each animal model of a condition still furthers basic biological understanding and do contribute a lot to therapeutic advancements.

Transgenic Mouse Service

Why don’t we use alternatives to replace animals for research?

Some animal protection societies require scientists to reduce, refine and replace the use of animals in research. And there are many methods and technologies invented to replace the use of animals, but completely eliminating animal research is not possible. Techniques, such as computer modeling, micro-dosing, MRI scanning and in vitro testing are boosted as alternatives to the use of live animals. However, every scientific method is designed for a very specific purpose and so those methods cannot replace each other. In vitro experiments, which are done with molecules or cell cultures, are very good to unravel mechanisms that happen inside the cell, but are not always so useful to find out how different tissues and organs interact inside the body. And for all those reasons, we will need to use live animals to answer some of the most important scientific questions related to human health.

How we reduce animals’ suffering in labs?

Researchers make every effort to minimize animals pain and suffering within labs. On one hand, many of the procedures carried out on animals involve no pain or discomfort, such as observing their behavior or collecting tissue samples after the animal is dead. On the other hand, when some procedures do involve pain or discomfort, some measures will be taken to alleviate their pain, such as using anesthesia and analgesia. Besides, research labs are also trying to provide animals with food, water and a clean, comfortable living environment. For more information about animal model visit website: CreativeAnimodel

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